Domperidone is a Medication that Acts as Peripherally Selective Antagonist of The dopamine d2 and d3receptors. It is Administered Orally, rectally, Or intravenously. Domperidone is Given in Order to Relieve nausea and vomiting; to Increase the Transit of Food Through The stomach (as A prokinetic agent Through Increase in Gastrointestinal Peristalsis); and to Increase lactation (breast Milk Production) By Release Of prolactin. It is also Used in the Scientific Study of the Way Dopamine (an Important neurotransmitter and hormone) Acts in the Body. The Uses Or indications of Domperidone Vary Between Nations. for Instance, in Italy It is Used in the Treatment Of gastroesophageal Reflux Disease and in Canada, the Drug is Indicated in Upper Gastrointestinal Motility Disorders and to Prevent Gastrointestinal Symptoms Associated with the Use of Dopamine Agonist Antiparkinsonian Agentsdomperidone is a Medicine that Increases the Movements or Contractions of the Stomach and Bowel. Domperidone is also Used to Treat Nausea and Vomiting Caused By other Drugs Used to Treat Parkinson's Disease.