Celecoxib is A cox-2 Selective nonsteroidal Anti-inflammatory Drug (nsaid). It is Used to Treat the Pain and Inflammation of Osteoarthritis, Rheumatoid Arthritis, ankylosing Spondylitis, acute Pain in Adults, Painful menstruation, and Juvenile Rheumatoid Arthritis. Celecoxib is Used For reduce the Number of Colon and Rectal Polyps in People With familial Adenomatous Polyposis. for Postoperative Pain, It is More or Less Equal To ibuprofen. for Pain Relief, It is Similar to Paracetamol (acetaminophen). and in Osteoarthritis Acetaminophen is the First Line Treatment for Oa. It is Originally Intended to Relieve Pain While Minimizing Gastrointestinal Adverse Effects Seen with Conventional Nsaids. in Practice, Its Primary Use is in People Who Need Regular and Long-term Pain Relief; Probably, No Advantage Exists to Using Celecoxib for Short-term or Acute Pain Relief Over Conventional Nsaids, Except in the Situation Where Nonselective Nsaids or Aspirin Cause Cutaneous Reactions (urticaria or "hives").