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Fluconazole Used for Treating and Preventing Certain Yeast and Fungal Infections. Fluconazole is An Azole Antifungal and Kills Sensitive Fungi By Interfering with the Formation of the Fungal Cell Membrane fluconazole is An Antifungal Medication that is Administered Orally or Intravenously. It is Used to Treat a Variety of Fungal Infections, Especially candida infections of the Vagina ("yeast Infections'), Mouth, Throat, and Bloodstream. It is also Used to Prevent Infections in People with Weak Immune Systems, Including Those with Neutropenia Due to Cancer Chemotherapy, Transplant Patients, Those with Advanced Hiv Infections, and Premature Babies. Its Mechanism of Action Involves Interfering with Synthesis of the Fungal Cell Membrane. Fluconazole, the First of a New Subclass of Synthetic Triazole Antifungal agents, is Available as Tablets for Oral Administration, as a Powder for Oral Suspension, and as a Sterile Solution for Intravenous Use in Glass and Plastic Containers.