Fexofenadine Hydrochloride


Fexofenadine Hydrochloride

Fexofenadine is a Non-sedating H1 Histamine Receptor Antagonist. Fexofenadine Hydrochloride, the Active Ingredient is A histamine h1-receptor Antagonist with the Chemical Name (±)-4-[1 Nylmethyl)-1-piperidinyl]-butyl]- Α, Α-dimethylhydroxy-4-benzeneacetic Acid Hydrochloride. Fexofenadine Hcl is the Hydrochloride Salt Form of Fexofenadine, a Carboxylated Metabolic Derivative Of terfenadine and Third Generation Selective histamine h1-receptor Antagonist with Antihistaminic and Non-sedative Effects. fexofenadine competitively Binds Peripheral H1-receptors, Thereby Stabilizing An Inactive Conformation of the Receptor. Consequently histamine binding and Activity as a Result of Mast-cell Degranulation Followed By the Release of Multiple Inflammatory Mediators, such as Interleukins, Prostaglandin and Leukotriene Precursors, is Blocked, Thereby Preventing the Triggering of Pro-inflammatory Pathways.

Details

  • Synonyms - 2-(4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl) Piperidin-1-yl) Butyl) Phenyl)- 2-methylpropanoic Acid Hydrochloride
  • Cas Number - 153439-40-8
  • Molecular Weight - 538.13
  • Molecular Formula - C32h40cino4
  • Fexofenadine Hydrochloride is a White to Off-white Crystalline Powder with Melting range of 195°C to 197 °C. It is Freely Soluble in Methanol and Ethanol, Slightly Soluble in Chloroform & Water, & Insoluble in Hexane.
  • Standard - Offered of Pharmaceutical Grade BP/USP/EP
  • Packing - Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements.


Molecular Structure

Molecular Structure