Losartan Potassium


Losartan Potassium

Losartan Potassium Is The Potassium Salt Of Losartan, Belongs To Non- Peptide Group- Angiotensin Ii Receptor Antagonist With Antihypertensive Activity. Losartan Selectively And Competitively Binds To The Angiotensin Ii Receptor (Type At1) And Blocks The Binding Of Angiotensin Ii To The Receptor, Thus Promoting Vasodilatation And Counteracting The Effects Of Aldosterone. Converted From Angiotensin I By Angiotensin-converting Enzyme (Ace), Angiotensin Ii Stimulates The Adrenal Cortex To Synthesize And Secrete Aldosterone, Decreasing Sodium Excretion And Increasing Potassium Excretion, And Acts As A Vasoconstrictor In Vascular Smooth Muscle. These Type Of Medications Work By Preventing The Constriction (Narrowing) Of Blood Vessels (Veins And Arteries). Losartan Was The First Angiotensin Ii Receptor Antagonist To Be Marketed. It Keeps Blood Vessels From Narrowing, Which Lowers Blood Pressure And Improves Blood Flow. Losartan Is Used To Treat High Blood Pressure (Hypertension). It Is Also Used To Lower The Risk Of Stroke In Certain People With Heart Disease. Losartan Is Used To Slow Long Term Kidney Damage In People With Type 2 Diabetes Who Also Have High Blood Pressure.

Details

  • Synonyms - Potassium [2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclo- Penta-2,5-dien-5-yl) Phenyl] Phenyl] Methyl] Imidazol-4-yl] Methanol
  • Cas Number - 124750-99-8
  • Mol.Formula - C22h22clkn6o
  • Mol.Weight - 461.01
  • It Is A White To Off-white Free-flowing Crystalline Powder With A Melting Range Of 184°c. It Is Freely Soluble In Water, Soluble In Alcohols.
  • Standard - Offered Of Pharmaceutical Grade BP/USP/EP
  • Packing - Offered In Export Worthy Packing Of 25 Kilos Or As Per Our Customer Requirements.


Molecular Structure

Molecular Structure